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Longevity Escape Velocity Foundation

— conducting and inspiring research to comprehensively cure and prevent human age-related disease.

“We are humanitarians first and foremost.”

— Dr. Aubrey de Grey

Projects

Robust Mouse Rejuvenation

Our flagship mouse longevity study will identify synergies between known rejuvenation therapies

Transplants On-Demand

We’re funding Keinice Bio’s novel cryopreservation technology to scale tissue and organ banking

Outreach & Events

Leadership

President & Chief Science Officer

Visionary biomedical gerontologist

Dr. Aubrey de Grey

Melissa King

Board Chair

Founding Executive Director, California Institute for Regenerative Medicine

David Wood

Executive Director

Veteran technology executive & futurist

News & Updates

In collaboration with primary author Professor Brian Kennedy, with input and enthusiastic endorsement from iconic researchers and leaders across the field of longevity medicine and allied fields, we are delighted to publish the Dublin Longevity Declaration: Consensus Recommendation to Immediately Expand Research on Extending Healthy Human Lifespans.

Combining rejuvenation interventions in rodents: a milestone in biomedical gerontology whose time has come

Our first peer-reviewed paper is now available to read free of charge.

Ever wondered what kind of planning goes into a study like LEVF's Robust Mouse Rejuvenation program? Our preparatory work included conducting a thorough survey of the data generated during past efforts to extend the healthy lifespan of rodents.

We're now making that information available to the community through the Rodent Aging Interventions Database (RAID) - a visual tool comparing the success achieved in published studies.

Robust Mouse Rejuvenation

Featured
March 31st, 2024

I mentioned last time that we were around the peak of absolute rate of death per week, and that this means there is expected to be a lot of noise at present, with groups changing places a lot in terms of proportion surviving. That's very much still true this month, as you can see…

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March 6th, 2024

Herewith RMR update #12! Nothing dramatic to report this time; we are at that tantalising phase where lots of mice are dying but not quite enough has happened to allow any firm conclusions. I've bitten the bullet and extended the plot area down to 0% survival - it seems like the right time to do that…

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February 3rd, 2024

I have seen (with great pleasure!) the rising recent interest in the survival curves as they have progressed to tentative interpretability. The story is basically unchanged this month…

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December 22nd, 2023

Here's RMR1 update #10, just in time for Christmas!

I don't have anything big to report this time other than updated survival curves, so let me instead start by highlighting that we have now posted a description of RMR2, the second in this series of mega-studies…

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Articles

The Case for: Senolytics
Jan 10, 2024

The first in a new series of articles by LEV Foundation’s Chief Science Monitor, Maximus Peto, introducing the interventions used in the first Robust Mouse Rejuvenation study and exploring the scientific rationale for their selection.